“CONCLUSIONS: The findings of this study demonstrate that premature infants have positive stools by EIA, viral culture, and RT-PCR at varying time points during 2 weeks following first-dose immunization with RV5. RT-PCR shedding rates need to be clinically evaluated in the context of virus quantification by cell culture, which was low. No symptomatic transmission to HHC {household contacts} was detected in this study, supporting low transmissibility of vaccine virus shed by these infants born prematurely.”

Vaccine 2011