Increased Risk of Noninfluenza Respiratory Virus Infections Associated With Receipt of Inactivated Influenza Vaccine

We randomized 115 children to trivalent inactivated influenza vaccine (TIV) or placebo. Over the following 9 months, TIV recipients had an increased risk of virologically-confirmed non-influenza infections (relative risk: 4.40; 95% confidence interval: 1.31-14.8). Being protected against influenza, TIV recipients may lack temporary non-specific immunity that protected against other respiratory viruses.

Among the 115 participants who were followed up, the median duration of follow-up was 272 days (interquartile range, 264–285 days), with no statistically significant differences in age, sex, household size, or duration of follow-up between TIV and placebo recipients (Table 1). We identified 134 ARI episodes, of which 49 met the more stringent FARI case definition. Illnesses occurred throughout the study period (Supplementary Appendix Figure 1). There was no statistically significant difference in the risk of ARI or FARI between participants who received TIV and those who received placebo, either during winter or summer 2009 (Table 2).

Clinical Infectious Diseases

Reproductive and Developmental Toxicity of Formaldehyde: A Systematic Review

“Meta-analysis showing that formaldehyde — a known carcinogen and and ingredient in most childhood vaccines — exposure causes reproductive and developmental harm, including spontaneous abortions in pregnancy at low doses. Most studies included are in animals that can have similar drug reactions as humans because human toxicity studies are not ethical.”

Mutation Research, 2011

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