Vaccine-related adverse events in Cuban children, 1999-2008.

“The DTwP vaccine exhibited the highest rate of adverse events. Common minor events were: fever (17,538), reactions at injection site (4470) and systemic side effects (2422). Rare events (by WHO definition) reported were: persistent crying (2666), hypotonic-hyporesponsive episodes (3), encephalopathy (2) and febrile seizures (112). Severe events included: anaphylaxis (2), respiratory distress (1), multiple organ failure (1), sudden death (1), vaccine-associated paralytic poliomyelitis (2), toxic shock syndrome (3), and sepsis (1). The 10 deaths and 3 cases of disability were investigated by an expert commission, which concluded that 8 of the 13 severe events were vaccination-related.” 

MEDICC Review 2012

Immunization triggering rheumatoid arthritis?

“We have recently observed a patient who developed Rhumatoid Arthritis three weeks after a second dose of tetanus toxoid. A 34 year old woman received two doses of tetanus toxoid in November and December 1986. A week after the second dose she developed severe pain with erythema and in duration measuring 10cm in diamater at the site of injection over the left deltoid muscle. This severe local reaction lasted 10 days. A few days after the erythema and induration started to fade the patient developed a symmetrical inflammatory polyarthritis involving proximal interphalangeal, metacarpophalangeal, wrist, elbow, shoulder, knee, and the metatarsophalangeal joints. The arthritis was severe with early morning stiffness lasting several hours. There was no past history of arthritis, inflammatory bowel disease, iritis, back pain, psoriassis, or recent infection and no family history of inflammatory arthritis.”


Is infant immunization a risk factor for childhood asthma or allergy?

“The Christchurch Health and Development Study comprises 1,265 children born in 1977. The 23 children who received no diphtheria/pertussis/tetanus (DPT) and polio immunizations had no recorded asthma episodes or consultations for asthma or other allergic illness before age 10 years; in the immunized children, 23.1% had asthma episodes, 22.5% asthma consultations, and 30.0% consultations for other allergic illness. Similar differences were observed at ages 5 and 16 years.”


Effects of diphtheria-tetanus-pertussis or tetanus vaccination on allergies and allergy-related respiratory symptoms among children and adolescents in the United States.

“The odds of having a history of asthma was twice as great among vaccinated subjects than among unvaccinated subjects. DTP or tetanus vaccination appears to increase the risk of allergies and related respiratory symptoms in children and adolescents.”

Journal of Manipulative and Physiological Therapeutics 2000

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