MRI findings in an infant with vaccine-associated paralytic poliomyelitis.

by | May 20, 2020 | Adverse Events, Paralysis, Polio Vaccines, Vaccine Failure, Vaccines

“We report a Brazilian infant who developed VAPP 40 days after receiving the first dose of oral polio vaccine (OPV). MR images of the cervical and thoracic spinal cord showed lesions involving the anterior horn cell, with increased signal intensity on T2-weighted sequences. We would like to emphasize the importance of considering VAPP as a differential diagnosis in patients with acute flaccid paralysis and an MRI showing involvement of medulla oblongata or spinal cord, particularly in countries where OPV is extensively administered.” 

Pediatric Radiology 2010

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